KO DirectorHorng-Huey Ko, PhD, Professor

  • ● Teaching Courses
    Undergraduate school:
    1.Aesthetic Hygiene (Lab)
    2.Regulation on Cosmetics
    3.Organic Chemistry
    4.Chemistry of Fragrance

    Graduate school:
    1.Special Topics on Natural Product

  • ● The Highest Education Degree
    Ph. D. in Graduate Institute of Pharmaceutical Science, Kaohsiung Medical University

  • ● Personal Experiences

  • 2015/08~present, Director, Department of Fragrance and Cosmetic Science, Kaohsiung Medical University

  • 2013/02~present, Professor, Department of Fragrance and Cosmetic Science, Kaohsiung Medical University

  • 2009/09- 2013/01, Associate Professor, Department of Fragrance and Cosmetic Science, Kaohsiung Medical University

  • 2003/08-2009/08, Assistant Professor, Department of Fragrance and Cosmetic Science, Kaohsiung Medical University

  • 2002/08-2009/07, Assistant Professor, Department of Cosmetic Science, Chung Hwa University of Medicinal Technology

  • 2002/02-2002/07, Assistant Professor, Department of Chemical Engineering, Yung Ta Institute of Technology and Commerce

  • 2001/08-2002/01, Assistant Professor, Department of Physical Therapy, Shu-Zen College of Medicine and Management

  • 2000/09-2001/07, Post-Doctoral Fellow in Graduate Institute of Pharmaceutical Science, Kaohsiung Medical University

    ● E-mail
    hhko@kmu.edu.tw

    ● TEL:07-3121101 ext.2643
       FAX:07-3210683

  • ● Research Area
    Natural Products Chemistry, Medicinal Chemistry, Functional Cosmetic and Food, Cosmetic Science

  • ● Recent Publications
    The most represented papers (2014~)

    1. C. L. Wang, T. H. Lan, C. W. Tzeng , C. C. Chang, T. C. Lin, H. H. Ko*, W. S. Hwang, H. H. Huang, F. L. Yen*, M. C. Wang*, Densification and Biocompatibility of Sintering 3.0 mol% Yttria-tetragonal ZrO2 Polycrystal Ceramics with x wt% Fe2O3 and 5.0 wt% Mica Powders Additive. Ceram. Int., 2017, 43, 1809-1818.
    2. C. I Chang, C. C. Chen, S. Y. Wang, C. Y. Chao, L. K. Chao, J. J. Chen, H. H. Koa, C. C. Chena, and Y. H. Kuo*,a, Three New Abietane-type Diterpenes from the Bark of Cryptomeria japonica. Helv. Chim. Acta, 2016, 99, 710–715. (a equal contribution)
    3. Z. C. Lin, C. W. Lee, M. H. Tsai, H. H. Ko, J. Y. Fang, Y. C. Chiang, C. J. Liang, L. F. Hsu, Stephen C. S. Hu*, and F. L. Yen*, Eupafolin Nanoparticles Protect HaCaT Keratinocytes from Particulate Matter-induced Inflammation and Oxidative Stress. Int. J. Nanomed., 2016, 11, 3907-3926.
    4. T. M. Lu* and H. H. Ko, A New Anthraquinone Glycoside from Rhamnus nakaharai and Anti-tyrosinase Effect of 6-Methoxysorigenin. Nat. Prod. Res., 2016, 30, 2655-2661. DOI: 10.1080/14786419.2016.1138300
    5. S. Y. Lin, H. H. Ko, S. J. Lee, H. S. Chang*, C. H. Lin, and I. S. Chen*, Biological Evaluation of Secondary Metabolites from the Root of Machilus obovatifolia. Chem. Biodivers., 2015, 12, 1057-1067.
    6. Y. J. Jin, C. C. Lin, T. M. Lu, J. H. Li, I. S. Chen, Y. H Kuo, and H. H. Ko*, Chemical Constituents Derived from Artocarpus xanthocarpus as Inhibitors of Melanin Biosynthesis. Phytochemistry, 2015, 117, 424-435.
    7. T. H. Lee, M. S. Lee, H. H. Ko, J. J. Chen, H. S. Chang, M. H. Tseng, S. Y. Wang, C. C. Chen, and Y. H. Kuo*, New Furanone and Sesquiterpene from the Pericarp of Calocedrus formosana. Nat. Prod. Commun., 2015, 10, 845-846.
    8. T. M. Lu*, H. H. Ko, L. T. Ng, and Y. P. Hsieh, Free Radical Scavenging, Anti-tyrosinase and Cellular Melanogenesis Inhibitory Activities of Synthetic Isoflavonoes. Chem. Biodivers., 2015, 12, 963-979.
    9. T. H. Lee, C. C. Chen, J. J. Chen, H. F. Liao a, H. S. Chang, P. J. Sung, M. H. Tseng, S. Y. Wang, H. H. Ko a, and Y. H. Kuo, New and Cytotoxic Components from Antrodia camphorate. Molecules 2014, 19, 21378-21385. (a equal contribution)
    10. F. J. Lin, F. L. Yen, P. C. Chen, M. C.Wang, C. N. Lin, C. W. Lee, and H. H. Ko*, HPLC-Fingerprints and Antioxidant Constituents of Phyla nodiflora. SCI World J. 2014, Volume 2014, Article ID 528653, 8 pages.
    11. Y. C. Ting, H. H. Ko, H. C. Wang, C. F. Peng, H. S. Chang, P. C. Hsieh, and I. S. Chen*, Biological Evaluation of Secondary Metabolites from the roots of Myrica adenophora. Phytochemistry, 2014, 103, 89-98.
    12. H. H. Ko a, Y. C. Chiang a, M. H. Tsai, C. J. Liang, L. F. Hsu, S. Y. Li, M. C. Wang, F. L. Yen*, and C. W. Lee*, Eupafolin, a Skin Whitening Flavonoid Isolated from Phyla nodiflora, Downregulated Melanogenesis: Role of MAPK and Akt pathways. J. Ethnopharmacol., 2014, 151, 386-393. (a equal contribution)

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